Endocrine Abstracts

Background: The most striking change in diabetes over recent years has been the convergence of previously distinctive phenotypes. Recently diagnosed children are younger, taller and with greater BM. Pediatric endocrinologists are facing with children presenting mixed signs of both diabetes types. So called hybrid diabetes, or type 1½ has insulin resistance in type 1 phenotype and vice versa autoimmunity in obese children.Patients and methods: Ten ch...

Hyperprolactinaemia is the most common disturbance in the pituitary gland function. Different physiological and patological conditions could influnce prolactin (PRL) secretion. Prolactin secreting tumors (micro and macroprolactinomas) are rare in children and adolescents (estimated incidence is 1 per milion). Functional diversity of prolactin action is responsable for different initial clinical expression of hyperprolactinaemia.We investigated causes of ...